Project title: NEURAL NETWORK PROCESSOR FOR CARDIAC PACEMAKERS

Company name : AI SEMI LTD.

TECHNOLOGICAL FIELD
Medical Devices

KEY WORDS
Congestive Heart Failure
(CHF), Cardiac Resynchronization Therapy (CRT), Atrioventricular
(AV) Delay, Interventricular (IV) Interval

PROJECT SUMMARY
AI SEMI develops a co-processor for implanted adaptive cardiac
resynchronization Therapy (CRT) device, based on it's patented
spiking neural network processor. The adaptive CRT device will
optimize online and continuously the atrioventricular (AV) delay
and interventricular (VV) interval for biventricular pacemakers
and defibrillators. In addition, AI SEMI develops an
optimization device for implanted CRT devices where the learning
module, the spiking neural network processor will optimize the
implanted CRT device from the external device that will be used
in hospitals and cardiac rehabilitation centers.

AI SEMI adaptive CRT device is expected to significantly improve
three major difficulties in current CRT devices:
1. Programming the CRT device,
2. Delivering Consistent CRT pacing and
3. Simplified follow-up procedure.

The expected end point result is a better hemodynamic performance
for CHF patients that will improve their quality of life. The
spiking neural network processor will have extremely low power
dissipation, which is critical for implanted cardiac pacemakers
devices.

ENTREPRENEURS
Dr. Rami Rom - CEO
Mr. Ehud Arad - Business Development Manager
Dr. Ran Ginosar - Head of VLSI lab, Electrical
Engineering, Technion
Dr. Cobbi Erel - MD, senior cardiologist,
Meir Hospital
Dr. Kobi Rosenblum - Neurobiologist, Haifa University
Dr. Michael Glikson - MD, Director of
electrophysiology & pacing unit, Sheba Hospital
Prof. Ofer Binah - Rappaport Institute, Haifa
Dr. Malka Yahalom - MD, Director of
electrophysiology unit, Galil Hospital.

PROJECT STATUS
Proof of concept using a software simulator of adaptive CRT
device (July, 2004). FPGA prototype of the spiking neural
network processor is planned for Q1 2005. Pre-clinical
experiment in cooperation with Prof. Landsberg, Technion, will be
carried out in Q1/Q2 2005.

COOPERATION REQUIRED
AI SEMI is looking for strategic partner and financial
investments.
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TEL: 972-4-6321478 972-52-3224091 EMAIL: AISemi@yozmot.org

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